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Myopia and Glaucoma May Share Genes: What a New Study Means for You

White and blue DNA double helix against a dark background
Key Takeaways (Quick Overview)

A 2026 meta-analysis of 34,825 people in Ophthalmology Science found that a higher genetic risk score for myopia was associated with higher odds of open-angle glaucoma. It does not mean that every short-sighted person will develop glaucoma, but people with high myopia should have regular eye examinations including optic nerve assessment.

Doctors have long known that people with significant myopia (short-sightedness) are more likely to develop glaucoma. New research suggests that part of the explanation may lie in shared genes.

What the study found

The study, published in Ophthalmology Science in October 2026 and highlighted by the American Academy of Ophthalmology, pooled individual data from 34,825 participants across six population-based cohorts and one high-myopia case-control study. Of these, 708 had open-angle glaucoma and 1,953 had high myopia.

  • Each standard deviation increase in a myopia genetic risk score was associated with higher odds of open-angle glaucoma (odds ratio 1.18).
  • Researchers identified 95 independent genetic locations associated with both conditions.

What it does not mean

This is an association. It does not mean that having glasses gives you glaucoma, and most short-sighted people will never develop it. The authors note limits as well, including that participants were predominantly of European ancestry, so we cannot assume the same size of effect in Indian patients. There is also no routine genetic test you need to request because of this study.

Why it still matters

Glaucoma often has no early symptoms, and it can be harder to spot in a highly myopic eye because the optic nerve already looks different. That is why a careful examination by an ophthalmologist is valuable.

What you can do

  • Have regular examinations if you have high spectacle power, and do not assume a new pair of glasses is the same as an eye check.
  • Tell your doctor about family history of glaucoma or high myopia.
  • Know the tests. Assessment may include eye pressure, gonioscopy, pachymetry, an OCT scan and a visual field test.
  • Stay active if your doctor agrees. A separate small observational study of 80 glaucoma patients, published in the Journal of Glaucoma, linked more physical activity with slower visual field loss. It cannot prove cause and effect, and exercise never replaces treatment.
  • Keep using prescribed drops, even when your eyes feel fine.

You can read more on our glaucoma treatment page.

Getting checked in Andheri West

Divyajyoti Eye Hospital is at Jyoti Apartment, Ground Floor, opposite the 7 Bungalows Bus Depot, J.P. Road, Andheri (West), Mumbai 400053. The OPD runs Monday to Saturday, 5:00 PM to 8:30 PM, and is closed on Sunday. Call +91-7777018301 or +91-88505 65588, or send an enquiry through our contact page.

Frequently asked questions

Does myopia cause glaucoma?

The study shows an association and possible shared genetics, not direct cause and effect. Most people with myopia never develop glaucoma, but high myopia is a recognised risk factor.

Should I get a genetic test?

This study does not change routine care, and no special genetic test is needed because of it. Regular eye examinations remain the practical step.

How often should someone with high myopia get checked?

Your eye doctor will advise based on your examination, power, age and family history.

Sources and further reading

This page is for general information and does not replace a consultation. Your own examination findings determine what is right for your eyes.

Topics Covered:
myopia glaucoma genetics high myopia glaucoma risk open angle glaucoma study 2026 glaucoma screening high power glasses eye check